Tiernan O’Malley, Prime Medicine

Tiernan O’Malley is the Head of Translational Medicine and Clinical Biomarkers at Prime Medicine, where he leads biomarker strategy and development, clinical pharmacology, and model-informed development across the company’s therapeutic programs. His work focuses on translating Prime’s gene editing modality into clinically meaningful measures of safety and efficacy, guiding data-driven decisions from discovery through early-phase trials.