Harold S. Bernstein, MD, PhD, Maze Therapeutics

Harold S. Bernstein M.D., Ph.D. brings more than three decades of experience and is an internationally recognized leader in basic scientific research, translational medicine and clinical development both in industry and academia. He currently serves as President, Head of Research and Development, and Chief Medical Officer at Maze Therapeutics, where he is shaping and contributing to the creative strategy and thorough scientific process aimed at delivering new, genetic-based medicines. Before joining Maze, Dr. Bernstein was Senior Vice President, Chief Medical Officer and Head of Global Clinical Development at BioMarin Pharmaceutical. Prior to that, he served as Head of Translational Medicine and Vice President of Global Medicines Development and Medical Affairs at Vertex Pharmaceuticals, and held roles of increasing responsibility at Merck and Co, including head of early development for Cardiometabolic Diseases. He was Professor of Pediatrics and a senior investigator at the Cardiovascular Research Institute and the Broad Center of Regeneration Medicine and Stem Cell Research at the University of California, San Francisco (UCSF). He also served as attending physician at UCSF Benioff Children’s Hospital in Pediatric Cardiology, and at the Mount Sinai Kravis Children’s Hospital in Cardiovascular Genetics. Dr. Bernstein currently serves as Adjunct Professor of Pediatrics and the Mindich Child Health and Development Institute at the Icahn School of Medicine at Mount Sinai. He studied biomedical science, human genetics, and medicine at the Mount Sinai School of Medicine, earning MPhil, PhD, and MD degrees, where he was inducted into the Alpha Omega Alpha honor society. He completed a pediatric residency, cardiology fellowship, and postdoctoral fellowship at UCSF and earned an undergraduate degree in biological sciences from Harvard College.