Gareth Lewis, PhD, GSK

Gareth Lewis is a Scientific Director within the Drug Metabolism & Pharmacokinetics (DMPK) modelling group at GlaxoSmithKline (GSK) in the UK currently working as a physiologically-based pharmacokinetic (PBPK) modeller. He joined GSK in 2003 after obtaining a BSc in Biochemistry (2001) from Cardiff University, Wales, with a year in industry at the former GlaxoWellcome. He’s since received a part-time PhD from University of Strathclyde, Glasgow, Scotland (2017). He has a broad range of DMPK experience from hands-on bench side to virtual bedside, and end-to-end study conduct, including in vitro assays, in vivo studies (organ perfusions, surgical PK & multiple isotope ADME), and the associated bioanalysis. This has supported his current role as a DMPK Development Project Rep and PBPK modeller integrating data for clinical translation, drug-drug interactions and special populations supporting projects from Candidate Selection to Registration for both NCE’s and biological platforms for a variety of diseases, such as Malaria and Tuberculosis in Global Health, immuno-infectious diseases like HIV with ViiV, or biological modalities in respiratory diseases. He has supported cross-pharma IQ consortia for Protein Binding and CYP3A Induction Modelling workpackages, the newly initiated Pregnancy & Lactation Modelling workstream, and currently co-chairs the Simcyp Members Discussion Group (SMDG). In his spare time he enjoys riding mountain bikes, cross-country running and now watching rugby.